MT-2 (Melanotan II)
10mg · Lyophilized Powder · Purity ≥99%
Melanotan II (MT-2) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), studied as a non-selective melanocortin receptor agonist across MC1R, MC3R, MC4R, and MC5R in pigmentation biology and CNS signalling research.
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Research Overview
Melanotan II's structural cyclisation imparts enhanced metabolic stability relative to the native α-MSH linear sequence, making it a widely used probe for melanocortin receptor pharmacology research. MC1R activation by MT-2 in melanocyte cell models has been studied in relation to eumelanin pathway stimulation and melanogenesis regulation. Separately, MC4R engagement has been investigated in the context of hypothalamic arousal pathways and energy balance signalling in CNS research models, reflecting the receptor's central expression profile. Supplied exclusively for laboratory and research use.
The melanocortin receptor family — MC1R through MC5R — mediates diverse physiological and signalling functions ranging from pigmentation to neuroendocrine regulation. Melanotan II, as a non-selective agonist of this receptor family, has served as a pharmacological tool in receptor subtype characterisation research, enabling parallel investigation of MC1R-driven melanogenesis and MC4R-driven central arousal and appetite signalling within the same compound model. Eumelanin synthesis pathway studies in cultured melanocyte models have used MT-2 to probe cAMP-PKA activation downstream of MC1R. All outcomes referenced pertain to preclinical models and do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | MT-2 (Melanotan II) |
| Format | Lyophilized Powder |
| Size | 10mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-MT210M-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $49.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-MT210M-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Melanotan II acetate lyophilized powder should be stored at −20°C in a sealed vial, protected from light and moisture to prevent oxidation and peptide degradation. Avoid repeated freeze-thaw cycles; prepare aliquots prior to initial reconstitution. Reconstituted solutions should be kept at 4°C and used within intervals consistent with laboratory protocols.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
Research Solution Reference Calculator
Pre-filled with 10mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
For research-use calculations only. Always verify measurements independently — not medical guidance.
Questions before you order?
Browse the FAQ for documentation, storage, and sourcing answers, or contact our support team directly. We aim to respond to all research procurement inquiries within one business day.

