COA Available
GLP-1 In Stock Research Use Only
Semaglutide
5mg · Lyophilized Powder · Purity ≥99%
Semaglutide is a long-acting, acylated synthetic GLP-1 receptor agonist peptide used extensively in preclinical metabolic biology research. Available in 5 mg and 10 mg lyophilized research vials at ≥99% purity.
$99.99 CAD
Purchase Options
Subscriptions can be managed from your customer account. Prices in CAD.
Research Overview
Semaglutide is a fatty-acid-acylated peptide analogue of the endogenous glucagon-like peptide-1 (GLP-1) hormone, engineered for enhanced plasma stability and extended half-life through albumin binding. Its structural modification over native GLP-1 makes it a widely referenced tool compound for investigating GLP-1 receptor (GLP-1R) signalling pathways, including insulin secretion dynamics, hypothalamic appetite-regulation circuits, and gastric motility modulation in preclinical models. GLP-1 receptors are expressed across multiple tissue types — including the pancreas, hypothalamus, and gastrointestinal tract — providing researchers with a broad range of mechanistic questions to explore using this compound. Supplied exclusively for laboratory and research use — not for human or animal consumption.
Preclinical literature has extensively characterised semaglutide's activity at the GLP-1 receptor, documenting its role as a high-affinity agonist with prolonged receptor engagement relative to native GLP-1. Published investigational studies have examined GLP-1R-mediated cAMP signalling, downstream insulin secretion amplification, and central nervous system pathways associated with energy homeostasis and satiety signalling in animal models. Semaglutide's enhanced proteolytic stability and albumin-binding profile have made it a preferred reference compound for comparative GLP-1R pharmacology research. All outcomes referenced pertain to preclinical or investigational models and do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | Semaglutide |
| Format | Lyophilized Powder |
| Size | 5mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-SEMAGL-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $99.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-SEMAGL-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Lyophilized semaglutide peptide should be stored at −20°C in a sealed, moisture-free environment upon receipt. Avoid repeated freeze-thaw cycles, as thermal cycling can degrade peptide integrity and reduce research-grade consistency. Once reconstituted, working solutions should be prepared under sterile laboratory conditions, stored at 4°C, and used within the timeframe established by your laboratory's standard operating procedures for peptide solutions.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
This product is supplied strictly for in-vitro and laboratory research use. It is not a drug, food supplement, or cosmetic and is not approved for human or veterinary clinical applications, diagnostics, or therapeutic use. Researchers are responsible for compliance with all applicable institutional and regulatory requirements in their jurisdiction.
Preparation Reference Guide
Research Solution Reference Calculator
Pre-filled with 5mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
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For research-use calculations only. Always verify measurements independently — not medical guidance.
Questions before you order?
Browse the FAQ for documentation, storage, and sourcing answers, or contact our support team directly. We aim to respond to all research procurement inquiries within one business day.
