Sermorelin Acetate
5mg · Lyophilized Powder · Purity ≥99%
Sermorelin acetate is the acetate salt form of GRF(1-29) NH₂, a 29-amino-acid synthetic peptide representing the shortest N-terminal fragment of endogenous human growth hormone-releasing hormone (GHRH) that retains full receptor activity. It binds GHRH receptors on pituitary somatotroph cells to stimulate GH gene transcription and pulsatile GH secretion, with release regulated by endogenous somatostatin feedback mechanisms.
Subscriptions can be managed from your customer account. Prices in CAD.
Research Overview
As the minimal active GHRH sequence, Sermorelin acetate provides a well-characterised reference standard for GHRH receptor pharmacology research, allowing investigators to study native-like receptor activation without the additional structural modifications present in newer GHRH analogues. The physiological somatostatin feedback loop governing GH release makes it a relevant model compound for neuroendocrine axis research examining signal regulation and negative feedback dynamics. BME Health supplies Sermorelin acetate at ≥98% purity by HPLC with full COA. Supplied exclusively for laboratory and research use.
Preclinical research has employed Sermorelin acetate in studies of GHRH receptor binding kinetics, somatotroph cAMP/PKA signalling, and GH gene transcription regulation. Its well-established structural relationship to native GHRH has made it a standard reference compound for comparing the pharmacological properties of newer GHRH analogues such as CJC-1295 and Tesamorelin in receptor affinity and signalling studies. Research into neuroendocrine feedback has also used Sermorelin as a tool to investigate somatostatin-mediated GH pulse regulation in pituitary explant and animal models. All outcomes referenced pertain to preclinical models and do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | Sermorelin Acetate |
| Format | Lyophilized Powder |
| Size | 5mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-SERMOR-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $99.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-SERMOR-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Store lyophilised Sermorelin acetate at −20°C in its original sealed vial, protected from moisture and light. Avoid repeated freeze-thaw cycles to maintain peptide integrity and biological activity in receptor assay systems. Reconstituted solutions should be aliquoted into single-use volumes and stored at −80°C; consult the lot-specific COA for stability guidance.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
Research Solution Reference Calculator
Pre-filled with 5mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
For research-use calculations only. Always verify measurements independently — not medical guidance.
Questions before you order?
Browse the FAQ for documentation, storage, and sourcing answers, or contact our support team directly. We aim to respond to all research procurement inquiries within one business day.

