COA Available
Longevity In Stock Research Use Only
5-Amino-1MQ
10mg · Lyophilized Powder · Purity ≥99%
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme highly expressed in adipose tissue that consumes S-adenosylmethionine (SAM) and methyl donors in the course of cellular energy metabolism. It is studied in preclinical research examining adipogenesis regulation, NAD+ pathway biology, and metabolic signalling in adipocyte and energy metabolism models.
$199.99 CAD
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Research Overview
NNMT has gained research attention as a metabolic regulator in adipose tissue, where its activity depletes the SAM methyl donor pool and modulates NAD+ precursor availability. 5-Amino-1MQ provides a pharmacological tool to inhibit NNMT activity in cell systems, enabling investigators to characterise the downstream consequences of NNMT inhibition on gene expression, lipid metabolism, and cellular energy state. Its small-molecule format supports applications in both cell-based assays and preclinical in-vivo metabolic studies. BME Health supplies 5-Amino-1MQ at research-grade purity with full COA. Supplied exclusively for laboratory and research use.
Preclinical research using 5-Amino-1MQ has focused on NNMT inhibition as a strategy to study adipocyte differentiation, lipid accumulation, and metabolic gene expression in cell culture models. Animal model studies have used NNMT inhibitors to investigate effects on adipose tissue mass and whole-body energy metabolism, examining the mechanistic link between SAM depletion and adipogenic programming. NAD+ pathway research has also incorporated 5-Amino-1MQ to probe the interplay between NNMT activity and NAD+ precursor availability in the context of metabolic disease models. All outcomes referenced pertain to preclinical models and do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | 5-Amino-1MQ |
| Format | Lyophilized Powder |
| Size | 10mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-5AMINO-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $199.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-5AMINO-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Store 5-Amino-1MQ at −20°C in its original sealed container, protected from light and moisture. The compound should be stored under inert conditions where possible, as small molecule quinolinium compounds may be sensitive to oxidative degradation. Avoid repeated freeze-thaw cycles; refer to the lot-specific COA for validated stability data and recommended reconstitution solvents.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
This product is supplied strictly for in-vitro and laboratory research use. It is not a drug, food supplement, or cosmetic and is not approved for human or veterinary clinical applications, diagnostics, or therapeutic use. Researchers are responsible for compliance with all applicable institutional and regulatory requirements in their jurisdiction.
Preparation Reference Guide
Research Solution Reference Calculator
Pre-filled with 10mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
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Questions before you order?
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